Page History

Table of Contents

The standardized uptake value (SUV) formulas are used in positron emission tomography (PET) analysis. Radiotracer concentration can be measured for any area-based region of interest (ROI) such as circle, square, polygon, etc. The SUV formulas depend on certain attributes in the DICOM image without which SUV values cannot be calculated.

This application provides the following SUV types

SUV Body Weight (SUV _bw)
SUV Lean Body Mass (SUV _lbm)
SUV Body Surface Area (SUV _bsa)

Note
N/A will be displayed in the event that SUV calculations are not available (e.g. due to missing DICOM attributes).

Image RemovedImage Added

1.

Required

data in

DICOM Attributes

General Tags

Tag

Tag	VR	VM	Description
(0010,0040)

	CS	1	Patient’s Sex
(0010,1020)

	DS	1	Patient’s Size
(0010,1030)

	DS	1	Patient’s Weight
(0008,0021)

	DA	1	Series Date
(0008,0031)

	TM	1	Series Time
(0008,0022)

	DA	1	Acquisition Date
(0008,0032)

	TM	1	Acquisition Time
(0028,0051)

	CS	1 - n	Corrected Image
(0054,1102)

	CS	1	Decay Correction
(0054,1001)

CS	1	Units
(0028,1052)

	DS	1	Rescale Intercept
(0028,1053)

DS

1

Rescale Slope

Radiopharmaceutical Information Sequence

Tag	Tag	VR	VM	Description
(0054,0016)

SQ

1

Radiopharmaceutical Information Sequence


	(0018,1074)	DS	1	Radionuclide Total Dose


	(0018,1078)	DT	1	Radiopharmaceutical Start DateTime


	(0018,1072)	TM	1	Radiopharmaceutical Start Time


	(0018,1075)	DS	1	Radionuclide Half Life

Manufacture’s
Manufacturer Tags

Tag

Tag	VR	VM	Description
(0009,100D)

	TM	1	Scan Time for GE (private tag)
(7053,1000)

	DS	1	SUV Scale Factor for Philips
(7053,1009)

DS

1

Activity Concentration Scale Factor for Philips

2.

SUV

formula

formulas

Main Formulas
- Body Weight (SUV _bw)

SUV _bw = $PET Image Pixels \times \frac{Weight(g)}{Radionuclide Total Dose \times Decay Correction}$ Image Removed

- [1]
  Image Added
- Body Surface Area (SUV _bsa)

SUV _bsa = $PET Image Pixels \times \frac{BSA}{Radionuclide Total Dose \times Decay Correction}$ Image Removed

- [1]
  Image Added
  with calibration factor = (mCi/ml)/(counts/pixels/sec), and BSA (m²) = (weight in kg)^0.425 x (height in cm)^0.725 x 0.007184
- Lean Body Mass (SUV _lbm)[2]
  SUV _lbm=

$PET Image Pixels \times \frac{LBM \times 1000}{Radionuclide Total Dose \times Decay Correction}$ Image Removed [2]Factors of Formula

- decay-corrected tissue concentration(kilobecquerels/mL)/(injected dose per g of lean body mass)
Factors
- Body Surface Area (BSA)
  BSA

= $Weight(kg)^{0.425} \times Height(cm)^{0.725} \times 71.84$ Image Removed

- (m²) = (weight in kg)^0.425 x (height in cm)^0.725 x 0.007184
- Lean Body Mass (Male)

Male = $(1.10 \times Weight(kg)) - (120 \times (\frac{Weight(kg)}{Height(cm)})^{2})$ Image Removed

Female = $(1.07 \times Weight(kg)) - (148 \times (\frac{Weight(kg)}{Height(cm)})^{2})$ Image Removed

Decay Correction

DecayCorrection = $2^{(\frac{-TimeGap}{Radionuclide Half Life})}$ Image Removed

Time Gap

TimeGap = $Scan Time - Radiopharmaceutical Start Time$ Image Removed

If Decay Correction(0054,1102) is ADMIN, TimeGap is 0.
If GE private tag has, Scan Time is with its value.

PET Image Pixels

PETImagePixels = $Rescale Slope \times Pixels + Rescale Intercept$ Image Removed

- lbm=1.10(weight in kg) − 120(weight in kg/height in cm)²
- Lean Body Mass (Female)
  lbm=1.07(weight in kg) − 148(weight in kg/height in cm)²

Spherical ROI Tool

Image Added

The Spherical ROI tool calculates SUV values based upon multiple slices (3D calculation) by considering all voxels within a sphere centered on the location where the tool is deployed.

The peak value option of this tool calculates the average value of voxels within a second sphere that is centered on the voxel with the highest value in the spherical ROI (the SUVmax voxel).

The Iso contours option identifies those pixels within the spherical ROI that are within a specified range.

[1]: Calculation of SUV _bw and SUV _bsa are according to the following equations, taken from Kim et al. Journal of Nuclear Medicine. Volume 35, No. 1, January 1994. pp164-167"Standardized uptake values of FDG: body surface area correction is preferable to body weight correction", https://pubmed.ncbi.nlm.nih.gov/8271040/
[2]: Calculation of SUV _lbm is according to Sugawara et al. Radiology, November 1999. pp 521-525. "Reevaluation of the standardized uptake value for FDG: variations with body weight and methods for correction", https://doi.org/10.1148/radiology.213.2.r99nv37521
[3]: O Et. Al. "Practical PERCIST: A Simplified Guide to PET Response Criteria in Solid Tumors 1.0", https://doi.org/10.1148/radiol.2016142043

Child pages

Versions Compared

Old Version 1

New Version Current